Firefighting is continuing at Harrington Junior School in Long Eaton.
Derbyshire Fire & Rescue Service received a call to attend a fire in the roof of the building at 12.12 hours.
The school was evacuated with everyone subsequently confirmed as safe and accounted for.
Firefighters from Long Eaton, Ilkeston and Ascot Drive with an aerial ladder platform are being supported by firefighters from Nottinghamshire’s Arnold, Highfields, London Road, and Stapleford stations.
A command support unit and water carrier are also assisting the incident from Leicestershire.
A brief statement has been posted on the school website - it said: "Our beautiful, vibrant school is on fire. No children in school today. All safe. Emergency services attending. Please stay away to help. I am heartbroken."
Members of the public have broken social distancing requirements to visit and view the scene. Meanwhile, Derby Road has been closed in both directions with congestion caused on both Petersham and Wilsthorpe Road as a result.
Six fire engines remain at the scene, supported by one aerial ladder platform, a water carrier, an incident command unit and a welfare unit to support crews on scene. Incident Commander, Group Manager Dean Gazzard said: “On arrival at the scene firefighters were faced with a well-developed fire in the roof of the building. Crews quickly got to work, surrounding the fire and have now brought the fire under control.
“Unfortunately two of our firefighters sustained minor injuries dealing with the fire and have been taken to hospital for treatment. We are continuing to work closely with partners including the Head Teacher of Harrington School, Erewash Borough Council, Emergency Planning, Public Health England and colleagues from Derbyshire police to bring the incident to the safest and quickest conclusion and we expect to be at the scene well into the evening.”
Local residents are being advised to keep windows and doors closed due to the smoke from the fire. People are also reminded to keep away from the incident in line with current government advice to stay alert and maintain social distancing.
An investigation into the cause of the fire will commence when it is safe to do so.
MP Maggie Throup has issued the following statement in the wake of the incident: “Following the devastating fire at Harrington Juniors earlier today, I have received a situation update from the Chief Fire Officer and have also spoken to the Local Education Authority and the Secretary of State.
“The main focus now is to make the site safe for pupils returning to schools on the same campus in the coming weeks and to begin the process of rebuilding Harrington as soon as possible.”